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Symbol Name ID |
Cacna2d2
calcium channel, voltage-dependent, alpha 2/delta subunit 2 MGI:1929813 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | nervous system phenotype |
increased susceptibility to pharmacologically induced seizures |
seizures |
myoclonus |
tonic seizures |
absence seizures |
abnormal spike wave discharge |
abnormal pituitary gland morphology |
absent lactotrophs |
abnormal cerebellum morphology |
abnormal Purkinje cell morphology |
Purkinje cell degeneration |
decreased Purkinje cell size |
cerebellum vermis hypoplasia |
abnormal axon morphology |
abnormal nervous system electrophysiology |
abnormal brain wave pattern |
abnormal neuron physiology |
abnormal CNS synaptic transmission |
abnormal miniature inhibitory postsynaptic currents |
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| Availability | Mouse Genotype | ||||||||||||||||||||
| Cacna2d2du-2J/Cacna2d2du-2J | * | ||||||||||||||||||||
| Cacna2d2du-3J/Cacna2d2du-3J | |||||||||||||||||||||
| Cacna2d2du-td/Cacna2d2du-td | |||||||||||||||||||||
| Cacna2d2ent/Cacna2d2ent | * | ||||||||||||||||||||
| Cacna2d2tm1Svi/Cacna2d2tm1Svi | |||||||||||||||||||||
| Cacna2d2du-2J/Cacna2d2+ | |||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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